A full service, phase I-IV clinical CRO
e-Clinical excellence
A reliable, cost-competitive solution


OPIS is a mid-sized CRO providing a full range of Clinical Research Services.
With 250 employees at the Headquarters in Italy, nine subsidiaries in Europe and
an extensive network of collaborators, we cover over 30 countries.

In its 19 years, OPIS has completed over 1100 clinical trials in various Therapeutic areas.
We offer flexible service models ranging from full-service packages to specific functional service options. OPIS follows a risk-based approach in the execution of all operational activities related to clinical studies. Not only do we assess risk factors related to Regulatory, medical and legal aspects, but we also carefully consider patient issues such as recruitment and well-being, time issues such as expected enrollment start and finishing points, quality issues such as proper audits and other risk factors related to study drug management and storage. Our monitoring activities have become centralized and we are able to reduce time and cost significantly. OPIS is interested in exploring partnerships in drug development through co-development models. OPIS currently has 30 active clients in the Pharmaceutical, Biotechnology, and Medical Device Industries. Our commitment to quality and continuous innovation has created long-lasting client relationships.
We collaborate closely with academic institutions and non-profit organisations for the advancement of medical science and OPIS has donated scholarships to promising students in the medical research field. Our integrity and ethical practices have earned us
the trust of sponsors, investigators and collaborators.

Coming together is a beginning, staying together is progress,
and working together is success.

Drawing inspiration from these words by Henry Ford, I reflect on 18 years as Head of OPIS.

OPIS is a company where coming together has meant actively participating in the creation of new therapeutic options for diseases. It has meant joining forces with skilled professionals, experts and above all, with courageous people. Thousands of patients courageous enough to want to make a difference to the lives of future patients, courageous Sponsors who embark on difficult and often uncertain journeys toward drug discovery and courageous clinical research staff and collaborators who by staying together have tackled infinite challenges and turned them into opportunities.

As people who value building professional relationships based on mutual respect and trust, we have worked with responsibility, clear communication and well-defined methods to execute projects in good clinical practice. I humbly acknowledge that progress and success can only be achieved by working together, as partner and team.

OPIS is a company driven by innovation with a personal touch. OPIS is a company where people matter, where every single person makes a difference and where change is made together.

I thank all of you who have come together, stayed together and worked together for the advancement of medical science and the pursuit of a better quality of life.”

 Aldo Poli, CEO 

Our Story

Continuous innovation to support growth

Clinical.NET version 3.0 released and validated
New subsidiaries in SE, CH
e-Management of protocol deviations, SAE, study drugs
New subsidiaries in D, FR
European expansion with subsidiaries in UK, B, ES, PL, RO
eClinical Study Portal
ISO 27001 Certification
Proprietary EDC System Validation
ISO 9001 Certification
First clinical research education courses
First audit by a big pharma
First contract with big pharma
Establishment of OPIS

Our Growth

Qualified Team

Aldo Poli

CEO & Co-founder of OPIS

MD degree from the University of Milan.
A reference point in Clinical Research Methodology, Trial design, Statistics and Biometrics.

Over 30 years of experience in the Pharmaceutical Industry and in Clinical Research.

Laura Ambrosoli

Medical Director Co-founder of OPIS

MD degree from School of Medicine and Surgery at the University of Pavia, Specialization in Clinical Pharmacology.

Over 20 years of experience in the Pharmaceutical Industry and in Clinical Research.

Chiara Costantini

Scientific Director, Head of Biometry

MSC in Statistics from the University of Rome.

Joined OPIS in 2015.

More than 20 years of experience in Biostatistics.

Raphaela Schnurbus

Clinical Solutions Director

Degree in Pharmaceutical Sciences from University of Heidelberg and a PhD in Molecular Biology from Ludwig-Maximilians University, Munich.

Joined OPIS in 2015.

More than 15 years in the Drug Development Industry.

Elisabetta Colombo

Director of Administration

Degree in Economics and Commerce from the University “Università Cattolica del Sacro Cuore di Milano”.

Joined OPIS in 2007.

More than 8 years in charge of general accounting and treasury management for OPIS.

Nadia Ambrosoli

Head of Clinical Operations

Graduated from the University of Milan.

Joined OPIS in 2002.

More than 15 years of experience in Clinical Research.

Vittoria Reggiani

Head of Quality

Graduated from the University “Università Cattolica del Sacro Cuore di Milano".

Joined OPIS in 2004.

Over 15 years of experience in Quality management and Clinical Trial management.

Fabio Renna

Head of Information and Communication Technology

Degree in Computer Science from the University of Milan.

Joined OPIS in 2005.

Over 10 years of experience IT architecture and software development, particularly in Clinical Research.

Irene Tagliabue

Head of General Affairs

Degree in Philosophy from the University of Milan.

Joined OPIS in 2006.

More than 10 years in charge of Information security systems and training.

Alessandro Poli

Strategic Advisor

Degree in Economic Science from L.U.de.S in Lugano.

Joined OPIS in 2005.

More than 10 years of executive support in OPIS.